Zinc enzymes

Roles of zinc ( l 1 ) ion in zinc enzymes

Zinc@) complexes of macrocyclic polyamines 1,2 and 3 make good models for zinc enzyme (e.g., carbonic anhydrase, alcohol dehydrogenase, phosphatase) active centers. Intrinsic acid properties of Zn** pertinent to the biological functions are disclosed. Zinc(II) ion is not only important kinetically but it also plays an indispensable role thermodynamically.

Introduction to Zinc Enzymes as Drug Targets

Effect of short-term zinc supplementation on zinc and selenium tissue distribution and serum antioxidant enzymes.

BACKGROUND A significant association between Zn and Se homeostasis exists. At the same time, data on the influence of zinc supplementation on selenium distribution in organs and tissues seem to be absent. Therefore, the primary objective of the current study is to investigate the influence of zinc asparaginate supplementation on zinc and selenium distribution and serum superoxide dismutase (SOD...

Reactivation in vitro of zinc-requiring apo-enzymes by rat liver zinc-thionein.

The ability of rat liver zinc-thionein to donate its metal to the apo-enzymes of the zinc enzymes horse liver alcohol dehydrogenase, yeast aldolase, thermolysin, Escherichia coli alkaline phosphatase and bovine erythrocyte carbonic anhydrase was investigated. Zinc-thionein was as good as, or better than, ZnSO(4), Zn(CH(3)CO(2))(2) or Zn(NO(3))(2) in donating its zinc to these apo-enzymes. Apo-(...

Zinc efficiency is correlated with enhanced expression and activity of zinc-requiring enzymes in wheat.

Zinc (Zn) is an essential micronutrient for plants. The ability of plants to maintain significant yields under low Zn is termed Zn efficiency (ZE) and its genetic and mechanistic basis is still not well understood. Previously, we showed that root Zn uptake did not play a role in ZE. In the current study, Zn-efficient and -inefficient wheat (Triticum aestivum) genotypes were grown for 13 d in ch...